| Titre |
Page |
Fichier
| Note |
| Preparation of 3-methyl-1-butyl ethanoate (pear essence) |
430 |
|
- |
| Preparation of (S)-butyl but-2-enoate |
433 |
|
- |
| Preparation of N-methylcyclohexanecarboxamide |
434 |
|
- |
| Protection of ketones as ethylene ketals (1,3-dioxolanes) |
436 |
|
- |
| Preparation of E-benzaldoxime |
437 |
|
- |
| Preparation of 4-bromoaniline |
439 |
|
Aniline : à éviter |
| Hydration of alkenes: preparation of hexan-2-ol from 1-hexene |
444 |
|
- |
| Stereospecific preparation of trans-cyclohexane-1,2-diol via bromohydrin and epoxide formation |
447 |
|
- |
| Preparation of cis-cyclohexane-1,2-diol by the Woodward method |
451 |
|
- |
| Asymmetric dihydroxylation of trans-stilbene |
453 |
|
- |
| Peracid epoxidation of cholesterol: 3-hydroxy-5a,6a-epoxycholestane |
455 |
|
- |
| The Sharpless epoxidation: asymmetric epoxidation of geraniol |
458 |
|
- |
| Hydration of alkenes by hydroboration-oxidation: preparation of octan-1-ol from 1-octene |
461 |
|
- |
| Preparation of 7-trichloromethyl-S-bromo-∆1-p-menthane by free radical addition of bromotrichloromethane to β-pinene |
462 |
|
- |
| Preparation of 1-iodobutane by SN2 displacement of bromide: the Finkelstein reaction |
465 |
|
- |
| Preparation of 4-bromomethylbenzoic acid by radical substitution and conversion to 4-methoxymethylbenzoic acid by nucleophilic substitution |
468 |
|
- |
| Reduction of benzophenone with sodium borohydride: preparation of diphenylmethanol |
473 |
|
- |
| Reduction of 4-t-butylcyclohexanone with sodium borohydride |
475 |
|
- |
| Stereospecific reduction of benzoin with sodium borohydride; determination of the stereochemistry by NMR spectroscopy |
477 |
|
- |
| Chemoselectivity in the reduction of 3-nitroacetophenone |
479 |
|
- |
| Reduction of diphenylacetic acid with lithium aluminium hydride |
481 |
|
- |
| Reduction of N-methylcyclohexanecarboxamide with lithium aluminium hydride: N-methylcyclohexylmethylamine |
484 |
|
- |
| Reduction of butyrolactone with diisobutylaluminium hydride and estimation by NMR of the relative proportions of 4-hydroxybutanal and its cyclic isomer 2-hydroxytetrahydrofuran in the product mixture |
485 |
|
- |
| Wollf-Kishner reduction of propiophenone to n-propylbenzene |
489 |
|
Hydrazine: à éviter |
| Preparation of Adams' catalyst and the heterogeneous hydrogenation of cholesterol |
491 |
|
- |
| Preparation of Wilkinson's catalyst and its use in the selective homogeneous reduction of carvone to 7,8-dihydrocarvone |
494 |
|
- |
| Birch reduction of 1,2-dimethylbenzene : 1.2-dimethyl-1,4-cyclohexadiene |
497 |
|
- |
| Reduction of ethyl 3-oxobutanoate using bakerw's yeast; asymmetric synthesis of (S)-ethyl 3-hydroxybutanoate |
498 |
|
- |
| Oxidation of 2-methylcyclohexanol to 2-methylcyclohexanone using aqueous chromic acid |
501 |
|
Sel de chrome (VI) : à éviter |
| Oxidation of menthol to menthone using aqueous chromic acid |
505 |
|
Sel de chrome (VI) : à éviter |
| Oxidation of 1-heptanol to heptanal using pyridinium chlorochromate |
507 |
|
Sel de chrome (VI) : à éviter |
| Preparation of 'active' manganese dioxide and the oxidation of cinnamyl alcohol to cinnamaldehyde |
510 |
|
- |
| Organic supported reagents: oxidations with silver(l) carbonate on Celite® |
513 |
|
- |
| Preparation of 2-aminobenzoic acid by Hofmann rearrangement of phthalimide |
515 |
|
- |
| Investigation into the stereoselectivity of the Beckmann rearrangement of the oxime derived from 4-bromoacetophenone |
518 |
|
- |
| Grignard reagents: addition of phenylmagnesium bromide to ethyl 3-oxobutanoate ethylene ketal |
523 |
|
- |
| Conjugate addition of a Grignard reagent to (S)-butyl but-2-enoate : preparation of (S)-butyl 3-methylheptanoate |
525 |
|
- |
| Acetylide anions: preparation of ethyl phenylpropynoate |
528 |
|
- |
| Generation and estimation of a solution of t-butyllithium and preparation of the highly branched alcohol tri-t-butylcarbinol |
529 |
|
- |
| Preparation of cinnamic acid |
535 |
|
- |
| Condensation of benzaldehyde with acetone: the Claisen-Schmidt reaction |
537 |
|
- |
| Synthesis of 5,5-dimethylcyclohexane-1,3-dione |
540 |
|
- |
| Reactions of indole: the Mannich and Vilsmeier reactions |
542 |
|
- |
| Preparation of 3-methylcyclohex-2-enone |
545 |
|
- |
| Enamines: acetylation of cyclohexanone via its pyrrolidine enamine |
546 |
|
- |
| Enol derivatives: preparation of the enol acetate, trimethylsilyl enol ether, and the pyrrolidine enamine from 2-methylcyclohexanone |
549 |
|
- |
| Reductive alkylation of enones: 2-(prop-2-enyl)-3-methylcyclohexanone |
553 |
|
- |
| Lithium diisopropylamide as base: regioselectivity and stereoselectivity in enolate formation |
555 |
|
- |
| Dianions: aldol condensation of the dianion from ethyl acetoacetate with benzophenone |
557 |
|
- |
| Preparation of E-stilbene with ylid generation under phase transfer conditions |
561 |
|
- |
| Preparation of 4-vinylbenzoic acid by a Wittig reaction in aqueous medium |
563 |
|
- |
| A Wittig reaction involving preparation and isolation of a stabilized ylid: conversion of 1-bromobutyrolactone to α-methylenebutyrolactone |
566 |
|
- |
| Preparation of (E,E)-1,4-diphenyl-1.3-butadiene |
569 |
|
- |
| Sulfur ylids: preparation of methylenecyclohexane oxide |
572 |
|
- |
| Illustration of 'umpolung' in organic synthesis: synthesis of ethyl phenylpyruvate via alkylation of ethyl 1,3-dithiane-2-carboxylate followed by oxidative hydrolysis with N-bromosuccinimide |
576 |
|
- |
| Nitration of methyl benzoate |
581 |
|
- |
| 4-Bromobenzophenone by the Friedel-Crafts reaction |
584 |
|
- |
| Friedel-Crafts acetylation of ferrocene using different Lewis acid catalysts and identification of the products by NMR |
586 |
|
- |
| Fries rearrangement of phenyl acetate: preparation of 2-hydroxyacetophenone |
589 |
|
- |
| Diels-Alder preparation of cis-cyclohex-4-ene-1,2-dicarboxylic acid |
591 |
|
- |
| Preparation of 2,3-dimethyl-1,3-butadiene and its Diels-Alder reaction with maleic anhydride |
594 |
|
- |
| Benzyne: Diels-Alder reaction with furan |
597 |
|
- |
| [2+2]-Cycloaddition of cyclopentadiene to dichloroketene: 7,7-dichlorobicyclo[3.2.0]hept-2-en-6-one |
600 |
|
- |
| Generation of dichlorocarbene and addition to styrene: preparation of (2,2-dichlorocyclopropyl)benzene |
603 |
|
Chloroforme : à éviter |
| Claisen rearrangement of allyl phenyl ether : preparation and reactions of 2-allylphenol |
605 |
|
Bromure d'allyle : à éviter |
| Preparation of 3,5-diphenyliaoxazoline by a 1,3-dipolar cycloaddition |
609 |
|
- |
| Isolation of eugenol, the fragrant component of cloves, and a colouring component of tomatoes |
613 |
|
- |
| Isolation and characterization of limonene; the major component of the essential cil of citrus fruit |
616 |
|
- |
| Isolation of caffeine from tea and theobromine from cocoa |
619 |
|
- |
| Dyes: preparation and use of indigo |
622 |
|
- |
| Synthesis of flavone |
624 |
|
- |
| Insect pheromones: synthesis of 4-methylheptan-3-ol and 4-methylheptan-3-one |
627 |
|
- |
| Insect pheromones: methyl 9-oxodec-2-enoate: the queen bee pheromone |
630 |
|
- |
| Synthesis of 6-nitrosaccharin |
633 |
|
- |
| Preparation of copper phthalocyanine |
636 |
|
- |
| Synthesis of tetraphenylporphin and its copper complex |
637 |
|
- |
| Observation of sensitized fluorescence in an alumina-supported oxalate system |
640 |
|
- |
| Synthesis of 2-[(2,4-dinitrophenyl)methyl]pyridine; a reversibly photochromic compound |
642 |
|
- |
| Preparation of 2,4,5-triphenylimidazole and conversion into its piezochromic and photochromic dimers |
644 |
|
- |
| Preparation and properties of the stabilized carbocations triphenylmethyl fluoborate and tropylium fluoborate |
647 |
|
- |
| Measurement of acid dissociation constants of phenols: demonstration of a linear free-energy relationship |
649 |
|
- |
| Measurement of solvent polarity |
652 |
|
- |
| Preparation of 1-deuterium-1-phenylethanol and measurement of a kinetic isotope effect in the oxidation to acetophenone |
654 |
|
- |
| Tautomeric systems |
658 |
|
- |
| Kinetic versus thermodynamic control of reaction pathways: study of the competitive semicarbazone formation from cyclohexanone and 2-furaldehyde |
659 |
|
- |
| Determination of an equilibrium constant by NMR spectroscopy |
662 |
|
- |
